Workplace Discrimination Assignment Example | Topics and Well Written Essays - 2500 words

Workplace Discrimination - Assignment Example According to Aronsom, racial discrimination comes from the word â€Å"race† that implies one takes advantage owing to their own prejudice or stereotype of their supremacy. In taking advantage; they may harm the person from a different race in various ways. Many conclude this discrimination in the words â€Å"The fight between blacks and whites† – excluding the brown race. This may be a result of some negative past experiences or some stereotypes formed from the beginning. Many strongly belief it is due to lack of education that adds to this problem of Racial Discrimination. This Racial Discrimination can be seen all around the society; streets, schools, colleges, public places and professional organizations. Fryer states that racial Discrimination at workplace is a problem that is growing over the time span; it not only creates problems within the organization but poses hazard to governments and other stakeholders of that organization. Racial discrimination is seen as a reason for the collapse of many organizations and it stands out today as a major problem owing to which many theories and strategies have been adopted by many organizations to prevent them from the turmoil of racism. As a result, the committee on the elimination of racial discrimination has laid great emphasis on the topic.... In order for such motivation to take place, it is crucial to avoid conflicts, especially racial conflicts as these once ignited, are difficult to stop. Such was the case in the recent riots of United Kingdom (2011). If we are to follow the process of efficiency for corporate entities, motivation is the key element that will lead to success as stated by the above figures who have each given out a different theory for motivation of workers (example: F.W Taylor’s Piece rate policy) (Stimpson, 2010) Racial Discrimination acts as a hindrance for many employees to be motivated and work efficiently; this racial discrimination has its roots either through past experiences or certain stereotypes inbuilt since a long time. Hindrance in work can jeopardize the whole operation of a corporation. It can start off with very minuet exposure and result in violence and chaos for the world to see (example 2011 UK riots) (Regrosa, 2011). There are various ways in which racial discrimination can t ake place at organizations; it can start off from the phase when an employee has not even secured a job with the company. Discrimination on basis of ethnicity or race during interviews is a common problem in many workplaces, therefore, with racial discriminatory Human Resource personnels; inefficiency in the â€Å"hiring process† should be no surprise. In fact some journals go to the extent of verifying that fact that African-Americans (blacks) at times have to work harder for the same job when competing with whites in the United States of America (Mottley, 1993). Asking a black person tougher questions, trying to embarrass a black, putting behind tougher situations or degrading a black while a professional

Role Of Notch Signaling In Oncogenesis Essay Example | Topics and Well Written Essays - 2250 words

Role Of Notch Signaling In Oncogenesis - Essay Example Extensive research in notch pathway has identified either dysregulation or faulty signaling in cancers and many other diseases like multiple sclerosis, tetralogy of Fallot and Alagille syndrome. Because Notch signaling pathway is involved in the progression and development of several malignancies, it is considered a novel therapeutic target and if the research on this aspect is fruitful, it can have the highest therapeutic impact in modern clinical medicine (Wang, Li, Banerjee and Sarkar, 2008).The Notch signaling pathway The most important constituents of the Notch signaling pathway are the receptors. There are basically four types of Notch receptors which are single- pass transmembrane receptor proteins. They are Notch1 through Notch 4. Each of these is a heterodimer which is proteolytically cleaved and lies at the surface of the cell. The receptor is made up of 2 domains, the ectodomain and intracellular domain. Both these domains are associated in a calcium dependent, noncovalent interaction. Ectodomain is large and constitutes the outside part of the cell surface. The intracellular domain is smaller and tethered to the membrane. The ectodomain part of Notch receptors interacts with certain ligands of adjacent cells. These ligands belong to Jagged and Delta- like families and are named as JAG1, JAG2, DLL1, DLL3, and DLL4. The interaction between the receptor and ligand induces a couple of proteolytic cleavages causing the release of the intracellular domain part of the receptor from the cell membrane.